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In spite of all current therapeutic advancements, a proportion of patients will however fail to respond and will be viewed as for curative therapy. At present, only allogeneic hematopoietic cell transplantation may be deemed perhaps curative, but it is also related to appreciable morbidity and mortality.
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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They can be uncommon in this malignancy when compared to other lymphoid neoplasms. CHD2
Some degree of immunophenotype overlap among the CLL, marginal zone lymphoma, and lymphoplasmacytic lymphoma exists. When the diagnosis is uncertain determined by peripheral blood circulation cytometry, lymph node biopsy really should be pursued.
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